Antimicrobial Resistance, Integron Carriage, and Fluoroquinolone Resistance Genes in Acinetobacte baumannii Isolates

Background: Acinetobacte is the leading cause of pneumonia and sepsis in ICU ward. Accordingly, present study, antibiotic susceptibility pattern, presence, dissemination different classes integrons fluoroquinolone resistance genes were investigated among A. baumannii isolates. Methods: In this descriptive, cross-sectional during a period 24 months (2018 - 2020), 100 isolates isolated from clinical specimens patients admitted to two teaching hospital Ardabil province northwest Iran. Kirby -Bauer disk diffusion, PCR, sequencing methods used for antimicrobial testing gene mutation verification. Results: The rates all tested antibiotics found be between 78% 100%. No isolate was resistant polymyxin B. Multidrug-resistant (MDR) rate about 99%. prevalence class 1, 2, 3 70%, 21%, 0%, respectively. aadA1 cassette detected 1 integron-carrying strains. Conclusions: High-level high observed these Our findings highlighted need continuous monitoring